Microorganisms and Disease

 

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Microorganisms and Disease

Question 1
Which of the following disease is caused by DNA viruses?
A
Poliomyelitis
B
Yellow fever
C
Measles
D
Small pox

Question 2
The influenza vaccine is administered each year because
A
mutations in the viral hemagglutinin may allow the virus to evade the immune response elicited by previous vaccines
B
it is a polysaccharide vaccine that does not confer long-term protection
C
the vaccine is sufficiently toxic to make it necessary to administer only a small amount at any one time
D
none of the above

Question 3
Each of the 3 virulence factors of Bacillus anthracis i.e. the capsule, edema toxin and lethal toxin can affect the activity of
A
B cells
B
macrophages
C
ciliated epithelial cells
D
M cells

Question 4
Which of the following statements is not true regarding Mycobacterium tuberculosis and/or the disease it causes?
A
The pathogen contains mycolic acid in its cell wall
B
The pathogen can live inside macrophages
C
Antibodies to the pathogen are protective
D
None of these

Question 5
The toxins produced by bacteria
A
kill viruses
B
encourage bacterial reproduction
C
interfere with physiological processes in the body
D
all of the above

Question 6
Mucus helps in protecting against pathogens by
A
lowering the pH
B
facilitating the growth of normal flora
C
blocking access and attachment of pathogens to mucosal surfaces
D
sequestering Iron

Question 7
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine?
A
The possession of a segmented RNA genome
B
A limited number of capsule types
C
The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings
D
The ability of the Rotavirus to be transmitted faster

Question 8
Type III secretion systems are used to inject "effector" proteins directly into a host cell. Salmonella uses a type III secretion system to help the pathogen to
A
survive the acid pH of the stomach
B
secrete LT (heat labile toxin) and ST (heat stable toxin) into the lumen of the intestine
C
survive within macrophages
D
activate T cells to proliferate and secrete cytokines

Question 9
A major difference between EHEC and EPEC is
A
EHEC secretes a Shiga-like toxin and EPEC does not
B
EHEC possesses a type III secretion system and EPEC does not
C
EPEC rearranges host cell actin and EHEC does not
D
EPEC passes through the placenta to infect the fetus and EHEC does not

Question 10
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?
A
Both organisms are gram-positive spore formers
B
Diphtheria toxin and edema toxin are ADP ribosylating toxins
C
The most serious disease symptoms are the direct result of toxin action
D
Both organisms cause skin and respiratory tract infections
There are 10 questions to complete.

 

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